The show's theme song, "Different Worlds," was written by Norman Gimbel and Charles Fox and performed by Maureen McGovern. "Different Worlds" peaked at #18 on the Billboard Hot 100 and spent two weeks at #1 on the Billboard adult contemporary chart, McGovern's only #1 on that chart.

The show was a ratings hit during its first half-season on air. It ranked fifth for the 1978-79 season with a 26.7 average household share, thanks in big part to Thursday night lead-in Mork & Mindy, which ranked No. 3. All of the top-five shows in 1978-79 were ABC comedies, with the others Laverne & Shirley (No. 1), Three's Company (No. 2) and Happy Days (tying Mork & Mindy at No. 3).

However, ratings for Angie dropped drastically after a move to Tuesday for the start of the 1979-80 season, even though the show was placed between Happy Days and Three's Company. (ABC moved Laverne & Shirley in an effort to bolster ratings on other nights.) Viewers lost interest in the interplay between the two lead characters after they were married in the season premiere, and many critics noted that much of the previously feisty chemistry that Pescow and Hays demonstrated on screen was apparently compromised once their characters were wed. The show was cancelled in its second season. Thirty-six episodes in total were produced.

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