Michigan and Michigan State advanced to the NCAA Division I Men's Basketball Tournament's Elite Eight on Friday night.

Second-seeded Michigan defeated Tennessee 74-71 in the Midwest Regional semifinals in Indianapolis, giving the Wolverines a Sunday date with Kentucky. The eighth-seeded Wildcats ousted the defending national champion Louisville Cardinals 74-69.

Fourth-seeded Michigan State outlasted top-seeded Virginia 61-59 in the East Regional semifinals in New York, giving the Spartans a Sunday date with Connecticut. The seventh-seeded Huskies defeated Iowa State 81-76.

Midwest Region

Michigan 73, Tennessee 71

Michigan's Jordan Morgan reacts after a play against Tennessee in the NCAA Division I Men's Baskeball Tournament Midwest Regional semifinals on Friday night at Lucas Oil Stadium in Indianapolis. (Photo: Andy Lyons/Getty Images)

Jordan Morgan's 15 points and seven rebounds led the Wolverines (28-8), who held off a furious second-half rally by the 11th-seeded Volunteers.

The Volunteers trailed by as many as 15 points in the second half before closing within 72-71 with under 15 seconds to play. Tennessee had an opportunity to take the lead, but Jarnell Stokes was called for a charge on Morgan with six seconds left.

Jordan McRae had a game-high 24 points for the Volunteers (24-13).

Kentucky 74, Louisville 69

Louisville Coach Rick Pitino shouts instructions to his team in the NCAA Division I Men's Basketball Tournament Midwest Regional semifinals in Indianapolis at Lucas Oil Stadium on Friday night. (Photo: Andy Lyons/Getty Images)

Aaron Harrison hit a go-ahead three-pointer with 39 seconds left and Julius Randle added two clutch free throws as the Wildcats defeated their in-state rivals for the second time this season.

Harrison, Randle and another freshman starter, Dakari Johnson, had 15 points apiece for Kentucky (27-10).

The Cardinals (31-6) were led by a pair of seniors, Russ Smith's 23 points and Luke Hancock's 19.Louisville Coach Rick Pitino fell to 11-1 in Sweet 16 games.

East Region

Michigan State 61, Virginia 59

Michigan State Coach Tom Izzo exhorts Matt Costello during the NCAA Division I Men's Basketball Tournament East Regional semifinal game against Virginia on Friday night at Madison Square Garden in New York. (Photo: Elsa/Getty Images)

Branden Dawson's 24 points and 10 rebounds led the Spartans (29-8) past the top-seeded Cavaliers.

Michigan State overcame a sluggish second-half start and withstood a late run by the Cavaliers (30-7). The Spartans held the Cavaliers (30-7) to 35.1 percent field-goal shooting.

Joe Harris and Malcolm Brogden both had 17 points for Virginia, the Atlantic Coast Conference regular-season and tournament champion which became the second No. 1 seed to be eliminated -- joining Wichita State.

Connecticut 81, Iowa State 76

Connecticut's Amida Brimah celebrates against iowa State in the NCAA Division I Men's Basketball Tournament's East Regional semifinals Friday night at Madison Square Garden in New York. (Photo: Elsa/Getty Images)

DeAndre Daniels' 27 points and 10 rebounds led the Huskies (29-8) past the Cyclones.

Daniels and teammates Shabazz Napier and Ryan Boatright dominated the game, pushing UConn out to a 36-26 lead at halftime. The Huskies extended their lead in the second half, but the Cyclones' DeAndre Kane and Monte Morris helped narrow the final margin of victory.

Dustin Hogue led Iowa State (28-8) with 34 points.