In 1989 the band released Cosmic Thing, their mainstream breakthrough, released on Reprise Records worldwide. The single "Channel Z", a single from the new album, became an alternative and college radio hit, hitting number one on the U.S. Hot Modern Rock Tracks chart, receiving significant airplay on MTV's modern rock show 120 Minutes.

The next single, "Love Shack", with its party vibe and colorful music video, became their first top-40 hit on the Billboard Hot 100, ultimately reaching #3 in November 1989. That peak was matched in March 1990 when their follow-up single, "Roam", also reached #3.  In Australia, the country that had most embraced the band a decade earlier, "Love Shack" stayed at number one for eight weeks.

Roam was #3 in 1989 - How about today?

A fourth single, "Deadbeat Club", which reminisced about the band's early days in Athens and whose video was shot on location and featured a cameo by fellow Athens artist R.E.M.'s Michael Stipe, reached #30. The Cosmic Thing album climbed into the U.S. top five and earned multi-platinum certification  it also had huge international success reaching #1 in both Australia and New Zealand and #8 in the UK. The group had a hugely successful world tour to support the record, and appeared on the cover of Rolling Stone in March, 1990.  In 1990 the B-52's were nominated for 4 MTV Video Music Awards including Video of the Year. They won two awards, Best Group Video and Best Art Direction.

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